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01-20-11 | Posted by


Options Abound for Canadians Seeking Injectable Treatments

As of spring 2010, there were over 30 approved dermal fillers on the Canadian market. For a traditionally conservative aesthetic culture- that’s more than a little overwhelming.

Canada’s history with filler dates back to the 1980s when Inamed (later Allergan) introduced a series of bovine purified bovine collagen fillers to the market. Though collagen products have largely fallen out of favour, Allergan’s Zyderm™, was discontinued in November 2010, collagen can be credited with popularizing injectables for smoothing of facial lines, wrinkles and the ever-popular lip plumping.

Enter Medicis. Since 2000, Medicis Inc. has virtually dominated the Canadian filler market with its duo of non-animal derived hyaluronic acids. Restylane®, popularly used for facial folds, wrinkles and superficial volume corrections and Perlane®, a thicker formulation best for lips and more significant volume deficits have been mainstays in the Canadian injectable market for over a decade. Both Restylane and Perlane work with the body’s natural hyaluronic acid to create volume at the site of injection and can last up to 6 months and one year, respectively.

Juvederm® (Allergan) is another stalwart in the Canadian filler market. Also made of hyaluronic acid (HA), Juvederm first became available in 2004 and now offers more than a dozen formulations featuring lidocaine and different viscosities for more specific effects and areas. Popularly combined with Allergan’s Botox for a scalpel-free “Soft Lift™” rejuvenation, Juvederm’s results can last up to a year depending on the injection.

It is Swiss innovation though, that has been a more recent force of change in the Canadian market. Teosyal® (Teoxane Laboratories) and a trio of HA fillers by Anteis (Esthelis®, Fortelis® and Mesolis®) both offer a range of injectables for small, medium and large volumes. With names like Teosyal Kiss, First Lines, Ultra Deep and Meso , Teoxane’s brand appeals to the increasing consumer savvy in Canada . Anteis, on the other hand, emphasizes ease of injection for the physician and a unique formulation for men-Esthelis Men-that capitalizes on the growing anti-aging interest among Canadian men.

The list of HAs goes on: Revanesse® (Prollenium Medical Technologies), Prevelle Silk ® (Mentor) and Elevess® (Anika Therapeutics)-each touting an advantage in price, pain management and precision-.are among the ever-changing, ever-growing body of hyaluronic acid fillers at Canadian physician’s finger tips.

For patients seeking a more durable touch up, there are semi-permanent fillers. Radiesse® (Merz Aesethetics) is made up of Calcium Hydroxylapetite (CaHa) a naturally occurring compound found in human bones. Radiesse works to both stimulate volume, like HA, and as an implant replacing lost volume in facial wrinkles, folds and other defects but is usually not advised for the lips. Results with Radiesse last up to 18 months and touch ups can be performed as soon as 2-4 weeks after the initial treatment.

Sculptra® (Sanofi Aventis) is a semi-permanent filler made of Poly-L-lactic Acid microspheres . Sculptra adds volume by stimulating your body to produce collagen in response to a foreign substance. Originally approved in Canada for facial lipoatrophy in HIV patients, Sculptra is now widely marketed for cosmetic indications. Patients usually receive two to three treatments over 6 weeks at an average cost of $2,000-$3,000.

The only permanent injectable available in Canada is Artesense. The next generation of Artecoll, Artesense adds permanent volume with Polymethylmethacrylate microspheres (PMMA) dissolved in a collagen solution and is considered an implant more than an injectable. Artesense is used as a longterm solution to wrinkles and other small volume deficits. Results begin to appear after about 90 days as the body’s natural collagen begins to replace the implanted solution. Patients who aren’t happy with the results of their initial treatment may return for touch ups as soon as two months after injection.

For those Canadians weary of injecting a foreign substance into their body, the Selphyl® Platelet Rich Plasma (PRP) System represents a totally new kind of dermal filler. Health-Canada approved since 2009, the Selphyl system uses the patient’s own fibroblasts (extracted through a punch biopsy) to culture millions of viable collagen stem cells that are in turn re-injected to fill small volume deficits like fine lines and acne scars. A form of autologous stem cell therapy, Selphyl does not pose the risk of allergic reaction and usually require about 3 treatments spaced 5 weeks apart.

But it’s not only the tremendous choice of fillers that’s driving the Canadian market. With billboards for Restylane on major city streets, it’s obvious that Canadians- like our cousins to the South- are quickly adopting dermal fillers as a means to stave and even prevent the signs of aging. With more and increasingly differentiated injectables available,  the right filler is that which suits your desired outcome, lifestyle and-most importantly- is delivered by a skilled and endorsed cosmetic professional.

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